Fig. 1 · Structure

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YJ196

NDM-1 Inhibitor

YJ196 is a selective inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1). It effectively interferes with the enzyme's function, thereby restoring the activity of β-lactam antibiotics against NDM-1-producing bacterial strains. This compound is valuable for research in antibiotic resistance and the development of novel therapeutic strategies targeting multidrug-resistant infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3035447-45-8
Applications NDM-1 Inhibitor
Formula C21H15N3O4S
Molecular Weight 405.43
SMILES
O=C(O)C1=NC2=C(NS(=O)(C3=CC=CC=N3)=O)C=CC(C4=CC=CC=C4)=C2C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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