YTP-17

Catalog No.: A44050
YAP-TEAD Inhibitor
YTP-17 is a potent inhibitor of the YAP-TEAD protein-protein interaction, exhibiting an IC50 of 4 nM. This compound demonstrates significant anti-tumor activity, making it a valuable tool for cancer research. YTP-17 can be utilized to investigate the role of the YAP-TEAD pathway in various tumorigenic processes.
Grouped product items
Size Price Stock Qty
1mg
$1,265.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionYTP-17 is a potent inhibitor of the YAP-TEAD protein-protein interaction, exhibiting an IC50 of 4 nM. This compound demonstrates significant anti-tumor activity, making it a valuable tool for cancer research. YTP-17 can be utilized to investigate the role of the YAP-TEAD pathway in various tumorigenic processes.
Product Information
Catalog NumA44050
FormulaC26H25ClF2N2O4
Molecular Weight502.94
CAS Number2714433-21-1
SMILESFC1=CC2=C([C@@]([C@@]3=C(C=CC(OCCO)=C3F)C(NC)=O)=C1Cl)C[C@](C4=CC=CC=C4)(CNC)O2
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