YZ129

Catalog No.: A13601

HSP90-calcineurin-NFAT inhibitor

YZ129

YZ129 Chemical Structure

CAS NO. 1643120-60-8

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.3 mL 166.49 mL 332.99 mL
0.5 mM 6.66 mL 33.3 mL 66.6 mL
1 mM 3.33 mL 16.65 mL 33.3 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13601
Actions Inhibitor
CAS No. 1643120-60-8
Formula C19H12N2O2
M. Wt 300.31
Purity >98%
Synonyms YZ 129, YZ-129
SMILES O=C(C1=CC=CC=C1C(NC2=CC=C(C=NC=C3)C3=C2)=C4)C4=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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