Fig. 1 · Structure
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Z-335 sodium
TXA2 Receptor Antagonist
Z-335 sodium is an orally active thromboxane A2 (TXA2) receptor antagonist. It demonstrates potent inhibition with IC50 values of 29.9 nM and 32.5 nM in human and guinea pig platelets, respectively. This compound is useful in studying the physiological and pathological roles of TXA2 in various conditions, including cardiovascular diseases and platelet aggregation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 146731-14-8 |
| Applications | TXA2 Receptor Antagonist |
| Formula | C18H17ClNNaO4S |
| Molecular Weight | 401.84 |
| SMILES | O=C(CC1=CC=C2C(CC(C2)CNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.