Fig. 1 · Structure

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(Z)-Aconitic acid

Glutamate Decarboxylase Inhibitor

(Z)-Aconitic acid serves as a potent inhibitor of glutamate decarboxylase, facilitating the regulation of neurotransmitter levels. This compound has demonstrated the ability to reduce IκB-α phosphorylation, which may have implications in inflammatory response modulation. Additionally, (Z)-Aconitic acid has been shown to inhibit antigen-induced arthritis and monosodium urate-induced gout, highlighting its potential utility in studies related to autoimmune and inflammatory diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 585-84-2
Applications Glutamate Decarboxylase Inhibitor
Formula C6H6O6
Molecular Weight 174.11
Synonyms cis-Aconitic acid
SMILES
O=C(O)/C([H])=C(C(O)=O)/CC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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