Z-Doxepin-d3 Hydrochloride

Catalog No.: A60137
Stable Isotope
Z-Doxepin-d3 Hydrochloride is a deuterated stable isotope of the active metabolite 7-Hydroxychlorpromazine hydrochloride, known for its dopaminergic activity. This compound enhances prolactin levels and dopaminergic turnover, leading to sedative effects in animal models. It is utilized in research focusing on psychosis and the modulation of amphetamine-induced stereotypic behaviors in rats, making it a valuable tool for studying neuropharmacological mechanisms.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-Doxepin-d3 Hydrochloride is a deuterated stable isotope of the active metabolite 7-Hydroxychlorpromazine hydrochloride, known for its dopaminergic activity. This compound enhances prolactin levels and dopaminergic turnover, leading to sedative effects in animal models. It is utilized in research focusing on psychosis and the modulation of amphetamine-induced stereotypic behaviors in rats, making it a valuable tool for studying neuropharmacological mechanisms.
Product Information
Catalog NumA60137
FormulaC17H14D6Cl2N2OS
Molecular Weight377.36
CAS Number2469242-68-8
SMILESClC(C=C1)=CC2=C1SC(C=C(O)C=C3)=C3N2CCCN(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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