Fig. 1 · Structure
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Z-Gly-Gly-Arg-AMC
Chromogenic Substrate
Z-Gly-Gly-Arg-AMC is a thrombin-specific chromogenic substrate that enables the study of thrombin generation in platelet-rich plasma (PRP) and platelet-poor plasma (PPP). This fluorogenic substrate has an excitation/emission maximum at 390/480 nm, facilitating sensitive detection of thrombin activity. It is widely utilized in research applications focused on coagulation and thrombotic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 66216-78-2 |
| Applications | Chromogenic Substrate |
| Formula | C28H33N7O7 |
| Molecular Weight | 579.60 |
| SMILES | CC=1C=2C(=CC(NC([C@@H](NC(CNC(CNC(OCC3=CC=CC=C3)=O)=O)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.