Fig. 1 · Structure
Documents & Downloads
Z-Leu-Arg-AMC
AMC
Z-Leu-Arg-AMC is a substrate specifically designed for the cysteine proteinase trypanopain-Tb derived from Trypanosoma brucei brucei. This 4-methylcoumarinyl-7-amide (Amc) leucine derivative features a carboxybenzoyl (Z) moiety, allowing for effective cleavage and fluorescence release. Its application in studying cysteine proteases makes it a valuable tool in proteomics and enzymology research, particularly in exploring the role of trypanopain in parasitic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 156192-32-4 |
| Applications | AMC |
| Formula | C30H38N6O6 |
| Molecular Weight | 578.66 |
| SMILES | CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)C=C1O3)=CC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.