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Z-Leu-Leu-Leu-fluoromethyl ketone

Cysteine Protease Inhibitor

Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a potent inhibitor of cysteine proteases. It has demonstrated effectiveness in inhibiting SARS-CoV infection and offers protective effects in mouse models against T. crassiceps challenges. This compound is instrumental in studies related to viral infection mechanisms and cysteine protease biology, making it a valuable tool for research in these areas.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	371167-61-2
Applications	Cysteine Protease Inhibitor
Formula	C₂₇H₄₂FN₃O₅
Molecular Weight	507.64
Synonyms	Z-LLL-FMK
SMILES	[C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)(C(N[C@H](C(CF)=O)CC(C)C)=O)CC(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.