(Z)-ONO 1301

Catalog No.: A63083
Isomer
(Z)-ONO 1301 is the isomer of ONO 1301, serving as an important experimental control in research. ONO 1301, a prostaglandin I2 mimetic, functions as a long-acting prostacyclin agonist with thromboxane-synthase inhibitory properties. It has been shown to enhance the production of hepatocyte growth factor (HGF) in multiple cell types and to improve ischemia-induced left ventricular dysfunction in murine, rat, and porcine models. This compound is valuable for studies focused on cardiovascular protection and tissue regeneration.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Z)-ONO 1301 is the isomer of ONO 1301, serving as an important experimental control in research. ONO 1301, a prostaglandin I2 mimetic, functions as a long-acting prostacyclin agonist with thromboxane-synthase inhibitory properties. It has been shown to enhance the production of hepatocyte growth factor (HGF) in multiple cell types and to improve ischemia-induced left ventricular dysfunction in murine, rat, and porcine models. This compound is valuable for studies focused on cardiovascular protection and tissue regeneration.
Product Information
Catalog NumA63083
FormulaC26H24N2O4
Molecular Weight428.48
CAS Number153814-74-5
SMILESOC(COC1=C2C(C(CCO/N=C(C3=CC=CC=C3)\C4=CN=CC=C4)=CCC2)=CC=C1)=O
Synonyms(Z)-ONO-AP 500-02
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