Z-TPE-2DEVD

Catalog No.: A25407
Caspase-3 Probe
Z-TPE-2DEVD is a selective probe for caspase-3, a key enzyme involved in the apoptotic pathway. This reagent exhibits a strong ability to bind to and detect active caspase-3, facilitating real-time monitoring of apoptosis. It is widely utilized in research applications involving cell death studies, drug development, and the evaluation of therapeutic interventions targeting apoptosis.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-TPE-2DEVD is a selective probe for caspase-3, a key enzyme involved in the apoptotic pathway. This reagent exhibits a strong ability to bind to and detect active caspase-3, facilitating real-time monitoring of apoptosis. It is widely utilized in research applications involving cell death studies, drug development, and the evaluation of therapeutic interventions targeting apoptosis.
Product Information
Catalog NumA25407
FormulaC78H94N18O24
Molecular Weight1667.69
CAS Number1426396-40-8
SMILESC(=C(\C1=CC=C(CN2C=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CCC(O)=O)=O)[C@H](C)C)=O)CC(O)=O)=O)C(N)=O)N=N2)C=C1)/C3=CC=CC=C3)(\C4=CC=C(CN5C=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)C(N)=O)N=N5)C=C4)/C6=CC=CC=C6
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