Z-VAD-CHO

Catalog No.: A25317
Caspase Inhibitor
Z-VAD-CHO is a potent, irreversible inhibitor of caspases, primarily targeting caspase-1 with a Ki value of 0.008 μM. This compound effectively modulates apoptotic pathways and is instrumental in studies related to inflammation and cell death. Z-VAD-CHO is widely utilized in research to investigate the role of caspases in various cellular processes and disease models.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-VAD-CHO is a potent, irreversible inhibitor of caspases, primarily targeting caspase-1 with a Ki value of 0.008 μM. This compound effectively modulates apoptotic pathways and is instrumental in studies related to inflammation and cell death. Z-VAD-CHO is widely utilized in research to investigate the role of caspases in various cellular processes and disease models.
Product Information
Catalog NumA25317
FormulaC20H27N3O7
Molecular Weight421.44
CAS Number875152-90-2
SMILESOC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O
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