Fig. 1 · Structure
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Zagociguat
Soluble Guanylate Cyclase Stimulator
Zagociguat is a soluble guanylate cyclase (sGC) stimulator that is orally active and penetrates the blood-brain barrier. This compound enhances intracellular levels of cGMP, leading to regulation of blood pressure, improved neuronal function, reduced inflammatory responses, and neuroprotective effects. Zagociguat is primarily utilized in research focused on neurodegenerative diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2201048-82-8 |
| Applications | Soluble Guanylate Cyclase Stimulator |
| Formula | C16H10F4N6 |
| Molecular Weight | 362.28 |
| Synonyms | CY-6463; IW-6463 |
| SMILES | FC1=C(CC2=NC(C3=NN=C(C(F)(F)F)N3)=CN4C=CN=C24)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.