Fig. 1 · Structure

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Zaltoprofen sulfoxide

Cat. No. A40124 CAS 134085-79-3

COX-2 Inhibitor/PPAR-γ Activator

Zaltoprofen sulfoxide is a selective COX-2 inhibitor with an IC50 of 45.38 nM, as well as a PPAR-γ activator. This compound effectively inhibits NF-κB and MAPK inflammatory signaling pathways, making it a valuable tool in the study of inflammation and acute lung injury models. It is particularly relevant for research focused on LPS-induced acute lung injury.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 134085-79-3
Applications COX-2 Inhibitor/PPAR-γ Activator
Formula C17H14O4S
Molecular Weight 314.36
SMILES
O=C(C(C)C1=CC=C2C(CC(C3=C(S2=O)C=CC=C3)=O)=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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