Fig. 1 · Structure
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Zamifenacin fumarate
M3 Receptor Antagonist
Zamifenacin fumarate is a potent antagonist of the muscarinic M3 receptor, primarily targeting the gastrointestinal system. It demonstrates significant efficacy in reducing colonic motility, making it relevant for research in conditions such as irritable bowel syndrome. This compound is essential for studies exploring gut motility modulation and the pharmacological mechanisms underlying gastrointestinal disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 127308-98-9 |
| Applications | M3 Receptor Antagonist |
| Formula | C31H33NO7 |
| Molecular Weight | 531.60 |
| Synonyms | UK-76654 fumarate |
| SMILES | OC(/C=C/C(O)=O)=O.N1(C[C@@H](CCC1)OC(C2=CC=CC=C2)C3=CC=CC=C3)CCC4=CC5=C(C=C4)OCO5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.