Fig. 1 · Structure
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Zamifenacin
M3 Receptor Antagonist
Zamifenacin is a potent antagonist of the muscarinic M3 receptor, demonstrating gut-selective activity. This compound effectively reduces colonic motility, making it a valuable tool in the study of irritable bowel syndrome and related gastrointestinal disorders. Its mechanism of action provides insights into the modulation of gastrointestinal function and potential therapeutic applications in digestive health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 127308-82-1 |
| Applications | M3 Receptor Antagonist |
| Formula | C27H29NO3 |
| Molecular Weight | 415.52 |
| Synonyms | UK-76654 |
| SMILES | N1(C[C@@H](CCC1)OC(C2=CC=CC=C2)C3=CC=CC=C3)CCC4=CC5=C(C=C4)OCO5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.