Fig. 1 · Structure
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ZD 2138
Cat. No.
A76448
CAS
140841-32-3
5-Lipoxygenase Inhibitor
ZD 2138 is a selective inhibitor of 5-lipoxygenase, an enzyme involved in the production of leukotrienes, which play a significant role in inflammation and bronchoconstriction. This compound has demonstrated potential in alleviating aspirin-induced bronchoconstriction, making it a valuable tool in asthma research and studies focused on respiratory disorders. Its application in modulating inflammatory pathways positions ZD 2138 as an important reagent for investigating therapeutic strategies in related pulmonary conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 140841-32-3 |
| Applications | 5-Lipoxygenase Inhibitor |
| Formula | C23H24FNO4 |
| Molecular Weight | 397.44 |
| SMILES | O=C1C=CC2=C(N1C)C=CC(COC3=CC(F)=CC(C4(CCOCC4)OC)=C3)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.