Fig. 1 · Structure
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ZD-6888 hydrochloride
Angiotensin II Antagonist
ZD-6888 hydrochloride is a potent angiotensin II antagonist that selectively interferes with the angiotensin II-mediated release of renin. This compound influences renal structure and function, making it a valuable tool for studying hypertension and cardiovascular diseases. Its application in research may enhance understanding of renal physiology and the modulation of the renin-angiotensin system in various pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 138620-17-4 |
| Applications | Angiotensin II Antagonist |
| Formula | C25H26ClN5O |
| Molecular Weight | 447.96 |
| Synonyms | ICI-D 6888 hydrochloride |
| SMILES | CCC1=NC2=C(CCCC2)C(OCC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.