Fig. 1 · Structure
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ZD-6888
Drug Derivative
ZD-6888 is a selective nitric oxide synthase inhibitor that primarily targets the endothelial nitric oxide synthase (eNOS) enzyme. This compound demonstrates significant biological activity by modulating nitric oxide levels, which makes it valuable in studies related to cardiovascular diseases, neuroprotection, and inflammation. ZD-6888 is used extensively in preclinical research to explore its therapeutic potential in various pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 138620-04-9 |
| Applications | Drug Derivative |
| Formula | C25H25N5O |
| Molecular Weight | 411.50 |
| Synonyms | ICI-D 6888 |
| SMILES | CCC1=NC2=C(CCCC2)C(OCC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.