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ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.92 mL | 94.59 mL | 189.18 mL |
| 0.5 mM | 3.78 mL | 18.92 mL | 37.84 mL |
| 1 mM | 1.89 mL | 9.46 mL | 18.92 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
*The above data is based on the productmolecular weight 528.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12242 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1542132-88-6 |
| Formula | C26H36N6O6 |
| M. Wt | 528.6 |
| Purity | >98% |
| Synonyms | ZED-1227, ZED1227, ZED 1227 |
| SMILES | O=C(OC)/C=C/CC[[email protected]](NC(C1=CN=CN1C)=O)C(NC2=CC=CN(CC(NCC(CC)CC)=O)C2=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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