ZED-1227

Catalog No.: A12242

transglutaminase 2 (TG2) inhibitor

ZED-1227

ZED-1227 Chemical Structure

CAS NO. 1542132-88-6

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.59 mL 189.18 mL
0.5 mM 3.78 mL 18.92 mL 37.84 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 528.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12242
Actions Inhibitor
M. Wt 528.6
Formula C26H36N6O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1542132-88-6
Synonyms ZED-1227, ZED1227, ZED 1227
SMILES O=C(OC)/C=C/CC[[email protected]](NC(C1=CN=CN1C)=O)C(NC2=CC=CN(CC(NCC(CC)CC)=O)C2=O)=O

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