Fig. 1 · Structure
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Zevotrelvir
Coronavirus Inhibitor
Zevotrelvir is a coronavirus inhibitor that targets the 3C-like (3CL) protease of SARS-CoV-2, demonstrating potent inhibitory activity with an IC50 of less than 0.1 mM. This compound is effective against the 229E hCoV strain and is valuable for research focused on coronavirus infections and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2773516-53-1 |
| Applications | Coronavirus Inhibitor |
| Formula | C28H26F3N5O3 |
| Molecular Weight | 537.53 |
| Synonyms | EDP-235 |
| SMILES | O=C1[C@@]2(CN([C@@H](C2)C#N)C([C@H](CC(C)C)N(C)C(C3=CC4=C(F)C=C(F)C(F)=C4N3)=O)=O)C5=CC=CC=C5N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.