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ZG-2492

LDHA Inhibitor

ZG-2492 is an orally active lactate dehydrogenase A (LDHA) inhibitor, exhibiting an IC50 of 156 nM. This compound effectively reduces lactate production, induces cell cycle arrest, and triggers apoptosis in pancreatic cancer cells. ZG-2492 demonstrates significant antitumor activity and serves as a valuable tool for research focused on pancreatic cancer and other related tumor types.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3084810-37-4
Applications	LDHA Inhibitor
Formula	C₂₀H₂₁ClN₄O₄S
Molecular Weight	448.92
SMILES	ClC1=CC=C(C#N)C=C1NS(C2=CC(N3CCN(CC3)CCC(O)=O)=CC=C2)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.