Fig. 1 · Structure

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Zidovudine O-β-D-glucuronide

Zidovudine Metabolite

Zidovudine O-β-D-glucuronide is a primary metabolite of Zidovudine, also known as 3'-Azido-3'-deoxythymidine β-D-glucuronide. This compound serves as a key indicator of Zidovudine metabolism and is utilized in research to study drug metabolism and pharmacokinetics. Its role as a metabolite can aid in understanding the efficacy and safety profiles of HIV treatments, particularly in the context of therapeutic drug monitoring.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 117675-21-5
Applications Zidovudine Metabolite
Formula C16H21N5O10
Molecular Weight 443.37
Synonyms 3'-Azido-3'-deoxythymidine β-D-glucuronide
SMILES
O=C1N(C=C(C(N1)=O)C)[C@@H]2O[C@@H]([C@H](C2)N=[N+]=[N-])CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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