Fig. 1 · Structure
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ZIF-8
Pyroptosis Inducer
ZIF-8 (2-Methylimidazole zinc salt) is a pyroptosis inducer that activates cell death via a caspase-1/gasdermin D (GSDMD)-dependent mechanism. This compound exhibits significant anticancer properties by mediating inflammatory cell death, making it a valuable tool for studying pyroptosis in cancer research. Its ability to influence cellular responses positions ZIF-8 as a promising candidate for investigations into therapeutic interventions targeting pyroptotic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 59061-53-9 |
| Applications | Pyroptosis Inducer |
| Formula | C8H10N4Zn |
| Molecular Weight | 227.59 |
| Synonyms | 2-Methylimidazole zinc salt |
| SMILES | CC1=NC=CN1[Zn]N2C=CN=C2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.