ZL0580

Catalog No.: A40265
HIV Inhibitor
ZL0580 is an HIV inhibitor that functions by selectively binding to the BD1 domain of BRD4, leading to epigenetic suppression of the virus. This compound effectively inhibits Tat transactivation and transcription elongation while promoting a repressive chromatin structure at the HIV promoter. ZL0580 is valuable for research applications focused on HIV therapies and the mechanisms of viral transcription regulation.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
5mg
$65.00
In stock
10mg
$105.00
In stock
25mg
$165.00
In stock
50mg
$245.00
In stock
100mg
$355.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZL0580 is an HIV inhibitor that functions by selectively binding to the BD1 domain of BRD4, leading to epigenetic suppression of the virus. This compound effectively inhibits Tat transactivation and transcription elongation while promoting a repressive chromatin structure at the HIV promoter. ZL0580 is valuable for research applications focused on HIV therapies and the mechanisms of viral transcription regulation.
Product Information
Catalog NumA40265
FormulaC25H23F3N4O4S
Molecular Weight532.53
CAS Number2377151-10-3
SMILESO=C(NC1=CC=C(S(N2CCC[C@H]2C(NC3=CC=CC=C3)=O)(=O)=O)C=C1)NC4=CC=C(C(F)(F)F)C=C4
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