Fig. 1 · Structure
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Zn(II) Mesoporphyrin IX
Heme Oxygenase Inhibitor
Zn(II) Mesoporphyrin IX is a potent inhibitor of heme oxygenase, particularly affecting the enzymatic activity in bone marrow. This compound demonstrates significant biological activity by inhibiting the growth of erythroid and myeloid progenitor cells, as well as blocking rhG-CSF-induced mobilization of these cells into peripheral blood. Zn(II) Mesoporphyrin IX is suitable for research applications involving hematopoietic regulation. However, its photochemical properties and potential toxicity to hematopoietic growth warrant careful consideration in experimental designs.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 14354-67-7 |
| Applications | Heme Oxygenase Inhibitor |
| Formula | C34H36N4O4Zn |
| Molecular Weight | 630.05 |
| Synonyms | ZnMP |
| SMILES | O=C(CCC1=C(C)C2=CC3=C(C)C(CC)=C4C=C5C(C)=C(CC)C6=[N]5[Zn+2]([N-]34)([N-]78)[N]2=C1C=C8C(CCC(O)=O)=C(C)C7=C6)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.