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ZN148

MBL Inhibitor

ZN148 is a synthetic metallo-β-lactamase (MBL) inhibitor that functions by chelating zinc, crucial for MBL activity. This compound effectively mitigates MBL-mediated carbapenem resistance, restoring susceptibility to carbapenems in over 98% of diverse clinical Enterobacterales strains. ZN148 is valuable for research in combating MBL-producing pathogenic bacteria and understanding resistance mechanisms in bacterial infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2190527-04-7
Applications	MBL Inhibitor
Formula	C₂₆H₃₃N₅O₆
Molecular Weight	511.57
SMILES	OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CN(C)C(C(C=N1)=CC=C1CN(CC2=CC=CC=N2)CC3=CC=CC=N3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.