Fig. 1 · Structure
Documents & Downloads
Zoledronate disodium
Apoptosi Inhibitor
Zoledronate disodium is a potent bisphosphonate that primarily functions as an apoptosis inhibitor, effectively inhibiting osteoclastogenesis and reducing bone turnover. This compound is particularly significant in managing Paget's disease of bone by suppressing metabolic activity and alleviating associated pain. Additionally, ongoing research, including the ZiPP trial, explores its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also demonstrates diverse anti-tumor effects in osteosarcoma, showcasing its multifunctional therapeutic applications in cancer research.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 131654-46-1 |
| Applications | Apoptosi Inhibitor |
| Formula | C5H8N2Na2O7P2 |
| Molecular Weight | 316.05 |
| Synonyms | CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium |
| SMILES | O=P(O)(C(CN1C=NC=C1)(P(O[Na])(O[Na])=O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.