Fig. 1 · Structure
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Zoniporide dihydrochloride
NHE-1 Inhibitor
Zoniporide dihydrochloride is a potent and selective inhibitor of the sodium hydrogen exchanger type 1 (NHE-1). This compound effectively inhibits NHE-1-dependent 22Na+ uptake in vitro, exhibiting an IC50 value of 14 nM. Zoniporide dihydrochloride has demonstrated antitumor activity, making it valuable for research applications focused on cancer therapeutics and cellular ion homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 241799-10-0 |
| Applications | NHE-1 Inhibitor |
| Formula | C17H18Cl2N6O |
| Molecular Weight | 393.27 |
| Synonyms | CP-597396 dihydrochloride |
| SMILES | N=C(N)NC(C1=C(C2CC2)N(C3=C4C(N=CC=C4)=CC=C3)N=C1)=O.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.