AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
Product Information
Catalog Num
A13587
Formula
C10H5N3O4
Molecular Weight
231.2
CAS Number
116313-73-6
SMILES
C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N
Synonyms
AG1288, AG 1288, Tyrphostin AG 1288
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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