Dynasore
Dynasore is a non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity
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Adooq Products cited in reputable paper
Adooq's Dynasore has been cited by 5 publications
- Umut Kerem Kolac, .et al. , Mol Biol Rep, 2023, Jan;50(1):493-506 PMID: 36352179
- KOLAC UK, .et al. , Research Square, 2022, 03 Jun
- Tsukamoto H, .et al. , J Biol Chem, 2018, Jun 29;293(26):10186-10201 PMID: 29760187
- Shigetoshi Yokoyama, .et al. , eLife, 2018, 7: e37854 PMID: 30526845
- Naoko Fujii, .et al. , J Biol Chem, 2016, Nov 18; 291(47): 24787-24799 PMID: 27733684
Biological Activity
| Description | Dynasore is a non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A12726 |
|---|---|
| Formula | C18H14N2O4 |
| Molecular Weight | 322.32 |
| CAS Number | 304448-55-3 |
| SMILES | C1=CC=C2C=C(C(=CC2=C1)C(=O)NN/C=C/3\C=CC(=O)C(=C3)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 60 mg/mL (186.15 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 3 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.03 mL | 155.13 mL | 310.25 mL |
| 0.5 mM | 6.21 mL | 31.03 mL | 62.05 mL |
| 1 mM | 3.1 mL | 15.51 mL | 31.03 mL |
| 5 mM | 0.62 mL | 3.1 mL | 6.21 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
