ETP-46464
ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
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Adooq Products cited in reputable paper
Adooq's ETP-46464 has been cited by 1 publications
- Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
Biological Activity
| Description | ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM. | ||
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Product Information
| Catalog Num | A13328 |
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| Formula | C30H22N4O2 |
| Molecular Weight | 470.52 |
| CAS Number | 1345675-02-6 |
| SMILES | CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5 |
| Synonyms | ETP46464, ETP 46464 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 6 mg/mL (12.75 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.25 mL | 106.27 mL | 212.53 mL |
| 0.5 mM | 4.25 mL | 21.25 mL | 42.51 mL |
| 1 mM | 2.13 mL | 10.63 mL | 21.25 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.25 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
