Fidaxomicin

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Catalog No. A13271

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Fidaxomicin 1mg A13271-1

Regular Price: $20.00

Special Price: $16.00

Fidaxomicin 2mg A13271-2

Regular Price: $30.00

Special Price: $24.00

Fidaxomicin 5mg A13271-5

Regular Price: $50.00

Special Price: $40.00

Fidaxomicin 10mg A13271-10

Regular Price: $65.00

Special Price: $52.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.

Fidaxomicin

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Chemical Information

Catalog Num A13271
Actions N/A
M. Wt 1058.04
Formula C52H74Cl2O18
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 873857-62-6
Synonyms N/A
SMILES code CC[[email protected]]1/C=C(\[[email protected]](C/C=C/C=C(/C(=O)O[[email protected]@H](C/C=C(/C=C(/C1O[[email protected]]2[[email protected]]([[email protected]]([[email protected]@H](C(O2)(C)C)OC(=O)C(C)C)O)O)\C)\C)[[email protected]@H](C)O)\CO[[email protected]]3[[email protected]]([[email protected]]([[email protected]@H]([[email protected]](O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)/C
Chemical Name N/A

Biological Activity

Description
Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.
Targets
RNA polymerase

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (94.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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