Icilin

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TRPM8 and TRPA1 activator

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Catalog No. A13560

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Icilin 10mg A13560-10
$60.00
Icilin 25mg A13560-25
$100.00
Icilin 50mg A13560-50
$220.00
Icilin 100mg A13560-100
$380.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)

Icilin

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Chemical Information

Catalog Num A13560
Actions Activator
M. Wt 311.3
Formula C16H13N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 36945-98-9
Synonyms AG 3-5
SMILES code C1C=C(NC(=O)N1C2=CC=CC=C2O)C3=CC(=CC=C3)[N+](=O)[O-]
Chemical Name 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one

Biological Activity

Description
Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)

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