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JNK Inhibitor
In Stock
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| Target | Activity | Value |
|---|---|---|
| JNK3 | IC50 | 0.7 nM |
| JNK1 | IC50 | 1.5 nM |
| JNK2 | IC50 | 2 nM |
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| A-375 | IC50 | 0.244 μM | Inhibition of JNK3-mediated c-jun phosphorylation in human A375 cells after 1 hr incubation | [PMID: 25415535] |
| HeLa | IC50 | 0.13 μM | Inhibition of JNK3-mediated c-jun phosphorylation in human HeLa cells after 1 hr incubation | [PMID: 25415535] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1408064-71-0 |
| Applications | JNK Inhibitor |
| Formula | C28H27N7O2 |
| Molecular Weight | 493.56 |
| Synonyms | JNK inhibitor |
| SMILES | CN(C)CC=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CN=CC=C4 |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
