Licofelone

Catalog No.: A11697
COX/LOX inhibitor
Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.
Grouped product items
Product Name Price Stock Qty
Licofelone 5mg
$54.00
In stock
Licofelone 10mg
$92.00
In stock
Licofelone 50mg
$270.00
In stock
Licofelone 100mg
$918.00
In stock
Licofelone 10mM * 1mL in DMSO
$135.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Licofelone has been cited by 1 publications
  • Silke Neumann, .et al. , Front Immunol, 2016, 7: 537 PMID: 27994586
  • Biological Activity
    Discription Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.
    Targets
    Target Value
    Product Information
    Catalog Num A11697
    Formula C23H22ClNO2
    Molecular Weight 379.88
    CAS Number 156897-06-2
    SMILES CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 16 mg/mL (42.11 mM)
    Water Insoluble
    Ethanol 3 mg/mL (7.89 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.32 mL 131.62 mL 263.24 mL
    0.5 mM 5.26 mL 26.32 mL 52.65 mL
    1 mM 2.63 mL 13.16 mL 26.32 mL
    5 mM 0.53 mL 2.63 mL 5.26 mL
    Useful Calculator

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