NG25

Catalog No.: A15185
TAK1/MAP4K2 inhibitor
NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.
Grouped product items
Product Name Price Stock Qty
NG25 5mg
$225.00
In stock
NG25 10mg
$425.00
In stock
NG25 25mg
$825.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.
Targets
Target Value
Product Information
Catalog Num A15185
Formula C29H30F3N5O2
Molecular Weight 537.58
CAS Number 1315355-93-1
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
Synonyms NG 25, NG-25
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 85 mg/mL (158.11 mM)
Water Insoluble
Ethanol 2 mg/mL (3.72 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.6 mL 93.01 mL 186.02 mL
0.5 mM 3.72 mL 18.6 mL 37.2 mL
1 mM 1.86 mL 9.3 mL 18.6 mL
5 mM 0.37 mL 1.86 mL 3.72 mL
Useful Calculator

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