PAC-1

Catalog No.: A11090
Caspase activator
PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM.
Grouped product items
Product Name Price Stock Qty
PAC-1 10mg
$40.00
In stock
PAC-1 50mg
$140.00
In stock
PAC-1 100mg
$250.00
In stock
PAC-1 200mg
$450.00
In stock
PAC-1 10mM * 1mL in DMSO
$50.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PAC-1 has been cited by 1 publications
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Biological Activity
    Discription PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM.
    Targets
    Target Value
    Product Information
    Catalog Num A11090
    Formula C23H28N4O2
    Molecular Weight 392.5
    CAS Number 315183-21-2
    SMILES C=CCC1=CC=C/C(=C/NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)/C1=O
    Synonyms PAC1,first procaspase activating compound
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 75 mg/mL (191.09 mM)
    Water Insoluble
    Ethanol 15 mg/mL (38.21 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.48 mL 127.39 mL 254.78 mL
    0.5 mM 5.1 mL 25.48 mL 50.96 mL
    1 mM 2.55 mL 12.74 mL 25.48 mL
    5 mM 0.51 mL 2.55 mL 5.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

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