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PR-171 (Carfilzomib)


Proteasome inhibitor

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Catalog No. A11278

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PR-171 5mg A11278-5

Regular Price: $50.00

Special Price: $45.00

PR-171 10mg A11278-10

Regular Price: $70.00

Special Price: $63.00

PR-171 25mg A11278-25

Regular Price: $100.00

Special Price: $90.00

PR-171 50mg A11278-50

Regular Price: $140.00

Special Price: $126.00

PR-171 10mM * 1mL in DMSO A11278-10mM-D

Regular Price: $75.00

Special Price: $67.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.

PR-171 (Carfilzomib)

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Chemical Information

Catalog Num A11278
Actions Inhibitor
M. Wt 719.9
Formula C40H57N5O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 868540-17-4
Synonyms PR-171-007
SMILES code CC(C)C[[email protected]@H](C(=O)[[email protected]]1(CO1)C)NC(=O)[[email protected]](CC2=CC=CC=C2)NC(=O)[[email protected]](CC(C)C)NC(=O)[[email protected]](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Chemical Name (S)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Biological Activity

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.
Proteasome (ANBL-6 cells)
5 nM


Solubility (25°C) * In vitro DMSO 50 mg/mL (69.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol/citrate vehicle 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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