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SB939 ( Pracinostat )

HDAC inhibitor

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Catalog No. A10830

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SB939 5mg A10830-5
SB939 10mg A10830-10
SB939 50mg A10830-50
SB939 100mg A10830-100
SB939 10mM * 1mL in DMSO A10830-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.

SB939 ( Pracinostat )

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Chemical Information

Catalog Num A10830
Actions Inhibitor
M. Wt 358.5
Formula C20H30N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 929016-96-6
Synonyms Pracinostat, SB-939
Chemical Name 3-​[2-​butyl-​1-​[2-​(diethylamino)ethyl]-​1H-​benzimidazol-​5-​yl]-​N-​hydroxy-​2E-​propenamide

Biological Activity

SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
Target Value
HDAC10IC50: 40nM
HDAC3IC50: 43nM
HDAC5IC50: 47nM
HDAC1IC50: 49nM
HDAC4IC50: 56nM
HDAC9IC50: 70nM
HDAC11IC50: 93nM
HDAC2IC50: 96nM
HDAC7IC50: 137nM
HDAC8IC50: 140nM
HDAC6IC50: 1.008μM
SIRT1IC50: >100μM


Solubility (25°C) * In vitro DMSO 72 mg/mL (200.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol 27 mg/mL (75.31 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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