SB939 ( Pracinostat )

SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
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Product Name Price Stock Qty
SB939 5mg
$90.00
In stock
SB939 10mg
$130.00
In stock
SB939 50mg
$400.00
In stock
SB939 100mg
$720.00
In stock
SB939 10mM * 1mL in DMSO
$124.00
In stock
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Adooq Products cited in reputable paper
Adooq's SB939 ( Pracinostat ) has been cited by 1 publications
  • Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
  • Biological Activity
    Discription SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
    Targets
    Target Value
    Product Information
    Catalog Num A10830
    Formula C20H30N4O2
    Molecular Weight 358.5
    CAS Number 929016-96-6
    SMILES CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)/C=C/C(=O)NO
    Synonyms Pracinostat, SB-939
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 68 mg/mL (189.68 mM)
    Water Insoluble
    Ethanol 26 mg/mL (72.52 mM)
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.89 mL 139.47 mL 278.94 mL
    0.5 mM 5.58 mL 27.89 mL 55.79 mL
    1 mM 2.79 mL 13.95 mL 27.89 mL
    5 mM 0.56 mL 2.79 mL 5.58 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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