Adooq's SB939 ( Pracinostat ) has been cited by 1 publications
Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
Biological Activity
Description
SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A10830
Formula
C20H30N4O2
Molecular Weight
358.5
CAS Number
929016-96-6
SMILES
CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)/C=C/C(=O)NO
Synonyms
Pracinostat, SB-939
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
68 mg/mL (189.68 mM)
Water
Insoluble
Ethanol
26 mg/mL (72.52 mM)
In vivo
1% DMSO+30% polyethylene glycol+1% Tween 80
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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