Sivelestat sodium salt

Neutrophil elastase inhibitor

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Catalog No. A14073

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Sivelestat sodium salt 10mg A14073-10
$70.00
Sivelestat sodium salt 25mg A14073-25
$140.00
Sivelestat sodium salt 50mg A14073-50
$240.00

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Quick Overview

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.

Sivelestat sodium salt

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Chemical Information

Catalog Num A14073
Actions Inhibitor
M. Wt 456.44
Formula C20H21N2NaO7S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 150374-95-1
Synonyms ONO-5046
SMILES code CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
Chemical Name N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium salt

Biological Activity

Description
Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.

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