Sivelestat sodium salt

Catalog No.: A14073
Neutrophil elastase inhibitor
Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
Grouped product items
Product Name Price Stock Qty
Sivelestat sodium salt 10mg
$70.00
In stock
Sivelestat sodium salt 25mg
$140.00
In stock
Sivelestat sodium salt 50mg
$240.00
In stock
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Adooq Products cited in reputable paper
Adooq's Sivelestat sodium salt has been cited by 1 publications
  • Shasha He, .et al. , Nature Biomedical Engineering, 2023, 7: 281-297
  • Biological Activity
    Discription Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
    Product Information
    Catalog Num A14073
    Formula C20H21N2NaO7S
    Molecular Weight 456.44
    CAS Number 150374-95-1
    SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
    Synonyms ONO-5046
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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