STF-62247 ON SALE Autophagy Inducer

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Catalog No. A10866

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
STF-62247 10mg A10866-10

Regular Price: $55.00

Special Price: $46.75

STF-62247 25mg A10866-25

Regular Price: $110.00

Special Price: $93.50

STF-62247 50mg A10866-50

Regular Price: $200.00

Special Price: $170.00

STF-62247 100mg A10866-100

Regular Price: $350.00

Special Price: $297.50

STF-62247 10mM * 1mL in DMSO A10866-10mM-D

Regular Price: $74.00

Special Price: $62.90

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).

STF-62247

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Chemical Information

Catalog Num A10866
Actions Inducer
M. Wt 267.4
Formula C15H13N3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 315702-99-9
Synonyms STF62247
SMILES code CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3
Chemical Name N-​(3-​methylphenyl)-​4-​(4-​pyridinyl)-​2-​thiazolamine

Biological Activity

Description
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).
Targets

Solubility

Solubility (25°C) * In vitro DMSO 53 mg/mL (198.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.22 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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