TCS PIM-1 4a

Pim inhibitor

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Catalog No. A11967

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TCS PIM-1 4a 10mg A11967-10
$65.00
TCS PIM-1 4a 25mg A11967-25
$150.00
TCS PIM-1 4a 50mg A11967-50
$265.00
TCS PIM-1 4a 10mM * 1mL in DMSO A11967-10mM-D
$82.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).

TCS PIM-1 4a

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Chemical Information

Catalog Num A11967
Actions Inhibitor
M. Wt 273.23
Formula C11H6F3NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 438190-29-5
Synonyms 0
SMILES code C1=CC(=CC(=C1)C(F)(F)F)/C=C\2/C(=O)NC(=O)S2
Chemical Name (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione thiazolidine-2,4-dione, 4a

Biological Activity

Description
TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).
Targets
Pim1
17 nM

Solubility

Solubility (25°C) * In vitro DMSO 55 mg/mL (201.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol 32 mg/mL (117.11 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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