Ticagrelor (AZD6140)

Catalog No.: A11238
P2Y12 antagonist
Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.
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Product Name Price Stock Qty
Ticagrelor 25mg
$50.00
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Ticagrelor 50mg
$80.00
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Biological Activity
Discription Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.
Product Information
Catalog Num A11238
Formula C23H28F2N6O4S
Molecular Weight 522.6
CAS Number 274693-27-5
SMILES CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO
Synonyms AZD 6140
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 99 mg/mL (189.45 mM)
Water Insoluble
Ethanol 52 mg/mL (99.51 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.14 mL 95.68 mL 191.35 mL
0.5 mM 3.83 mL 19.14 mL 38.27 mL
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL
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