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Biological Activity
MRS 2578 is a selective antagonist of P2Y6 nucleotide receptors
Targets
| P2Y6 | ||||
| 37 nM |
| In vitro (25°C) | DMSO | 39 mg/mL (82.5 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.16 mL | 105.78 mL | 211.55 mL |
| 0.5 mM | 4.23 mL | 21.16 mL | 42.31 mL |
| 1 mM | 2.12 mL | 10.58 mL | 21.16 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.23 mL |
*The above data is based on the productmolecular weight 472.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11486 |
|---|---|
| Actions | Antagonist |
| CAS No. | 711019-86-2 |
| Formula | C20H20N6S4 |
| M. Wt | 472.7 |
| Purity | >98% |
| Synonyms | MRS2578 |
| SMILES | C1=CC(=CC(=C1)NC(=S)NCCCCNC(=S)NC2=CC=CC(=C2)N=C=S)N=C=S |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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