Y-27632 2HCl

On Sale
Catalog No.: A11001
ROCK Inhibitor
Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
Grouped product items
Product Name Price Stock Qty
Y-27632 5mg
Special Price $30.00 Regular Price $45.00
In stock
Y-27632 10mg
Special Price $50.00 Regular Price $65.00
In stock
Y-27632 25mg
Special Price $80.00 Regular Price $100.00
In stock
Y-27632 50mg
Special Price $140.00 Regular Price $190.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Other Forms of Y-27632 2HCl

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Y-27632 2HCl has been cited by 34 publications
  • Johannes Robert Fleischer, .et al. , Mol Cancer, 2023, Jan 24;22(1):17 PMID: 36691028
  • Vignesh Jayarajan, .et al. , Cells, 2023, Jan 17;12(3):346 PMID: 36766688
  • Heming Ning, .et al. , In Vitro Cell Dev Biol Anim, 2023, Jun;59(6):410-419 PMID: 37405627
  • Eric Lian, .et al. , STAR Protoc, 2023, May 22;4(2):102314 PMID: 37220001
  • Stephanie T Pohl, .et al. , Methods Mol Biol, 2023, 2584:371-387 PMID: 36495461
  • Charlotte Phelps, .et al. , Am J Physiol Cell Physiol, 2023, Mar 1;324(3):C787-C797 PMID: 36689673
  • Shunsuke Murakami, .et al. , Regen Ther, 2022, Nov 25;21:574-583 PMID: 36475025
  • Sergio Pedraza-Arevalo, .et al. , STAR Protoc, 2022, Aug 30;3(3):101656 PMID: 36092820
  • Ji-Hyun Lee, .et al. , Cell Stem Cell, 2022, May 5; 29(5): 826-839 PMID: 35523142
  • Adam Pietrobon, .et al. , Cell Rep, 2022, Jul 5;40(1):111048 PMID: 35793620
  • Sarkawt Hamad, .et al. , Stem Cell Res Ther, 2022, Jun 11;13(1):251 PMID: 35690874
  • Stasia Krishtul, .et al. , Polym Adv Technol, 2022, 33( 11): 3842-3852
  • Peter T Ruane, .et al. , Hum Reprod, 2022, Apr 1;37(4):777-792 PMID: 35079788
  • Takayuki Miyoshi, .et al. , J Gastroenterol, 2022, Jun;57(6):441-452 PMID: 35294680
  • Ana-Maria Cujba, .et al. , Cell Rep, 2022, Mar 1;38(9):110425 PMID: 35235779
  • Dan Zhao, .et al. , Poult Sci, 2022, Mar; 101(3): 101642 PMID: 35016046
  • Antigoni Gogolou, .et al. , Curr Protoc, 2021, Jun;1(6):e137 PMID: 34102038
  • Tiago De Oliveira, .et al. , Cancers (Basel), 2021, Mar 2;S2451-9456(21)00095-7 PMID: 33671096
  • Denise Muller, .et al. , BMC Med, 2021, Nov 16;19(1):300 PMID: 34781947
  • Ayumi Horikawa, .et al. , PloS one, 2021, Jul 12;16(7):e0254373 PMID: 34252142
  • Hayato Mizuta, .et al. , Nat Commun, 2021, Feb 24;12(1):1261 PMID: 33627640
  • Scott Bell, .et al. , Stem Cell Reports, 2021, Jul 13;16(7):1749-1762 PMID: 34214487
  • Shenyang Li, .et al. , J Cell Mol Med, 2020, Dec 20;25(2):1207-1220 PMID: 33342057
  • Takao FUCHIGAMI, .et al. , J Appl Oral Sci, 2020, 28: e20190558 PMID: 32348439
  • Jing-Yu Lin, .et al. , Cell Discov, 2020, 6: 20 PMID: 32284878
  • Yu Huang, .et al. , Stem Cells Int, 2019, 2019: 3975689 PMID: 31565060
  • XinYan, .et al. , Stem Cell Res, 2019, May 17 PMID: 31141763
  • Daniela F. Duarte Campos, .et al. , J Biomed Mater Res A, 2019, April 22 PMID: 31012205
  • Scott Bell, .et al. , Am J Hum Genet, 2019, May 2;104(5):815-834 PMID: 31031012
  • Ooi J, .et al. , Cell Rep, 2019, Feb 26;26(9):2494-2508 PMID: 30811996
  • Scott Bell, .et al. , Stem Cell Reports, 2018, Jul 10; 11(1):183-196 PMID: 29937144
  • Christina Zarouchlioti, .et al. , Am J Hum Genet, 2018, Apr 5; 102(4): 528-539 PMID: 29526280
  • Ai Takemoto, .et al. , Sci Rep, 2017, 7: 42186 PMID: 28176852
  • Scott Bell, .et al. , Stem Cells Transl Med, 2017, Mar; 6(3): 886-896 PMID: 28170165
  • Biological Activity
    Discription Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
    Targets
    Target Value
    Product Information
    Catalog Num A11001
    Formula C14H21N3O.2HCl
    Molecular Weight 320.3
    CAS Number 146986-50-7, 129830-38-2
    SMILES C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 61 mg/mL (190.46 mM)
    Water 13 mg/mL (40.59 mM)
    Ethanol Insoluble
    In vivo saline 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.22 mL 156.1 mL 312.21 mL
    0.5 mM 6.24 mL 31.22 mL 62.44 mL
    1 mM 3.12 mL 15.61 mL 31.22 mL
    5 mM 0.62 mL 3.12 mL 6.24 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Y-27632 2HCl | Y-27632 2HCl Supplier | purchase Y-27632 2HCl | Y-27632 2HCl cost | Y-27632 2HCl manufacturer | order Y-27632 2HCl | Y-27632 2HCl distributor | buy 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 Supplier | purchase 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 cost | 146986-50-7, 129830-38-2 manufacturer | order 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 distributor