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Y-27632 2HCl


ROCK Inhibitor

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Catalog No. A11001

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Y-27632 5mg A11001-5

Regular Price: $60.00

Special Price: $54.00

Y-27632 10mg A11001-10

Regular Price: $90.00

Special Price: $81.00

Y-27632 25mg A11001-25

Regular Price: $180.00

Special Price: $162.00

Y-27632 50mg A11001-50

Regular Price: $260.00

Special Price: $234.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).

Y-27632 2HCl

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Chemical Information

Catalog Num A11001
Actions Inhibitor
M. Wt 320.3
Formula C14H21N3O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 146986-50-7, 129830-38-2
Synonyms N/A
SMILES code C[[email protected]](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
Chemical Name trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

Biological Activity

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
ROCK1 (p160ROCK) (Cell-free assay) ROCK2 (Cell-free assay)
140 nM(Ki)300 nM(Ki)


Solubility (25°C) * In vitro DMSO 64 mg/mL warmed (199.83 mM)
Water 14 mg/mL (43.71 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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