1-Methoxyphaseollidin is a flavonoid that functions as a lysoPAF acetyltransferase inhibitor, exhibiting an IC50 of 48 μM. This compound demonstrates significant antibacterial activity against Helicobacter pylori, including strains resistant to clarithromycin and amoxicillin, as well as several clarithromycin-sensitive strains. Its potential applications extend to research in antibiotic resistance and the development of new antibacterial therapies.
1-Methoxyphaseollidin is a flavonoid that functions as a lysoPAF acetyltransferase inhibitor, exhibiting an IC50 of 48 μM. This compound demonstrates significant antibacterial activity against Helicobacter pylori, including strains resistant to clarithromycin and amoxicillin, as well as several clarithromycin-sensitive strains. Its potential applications extend to research in antibiotic resistance and the development of new antibacterial therapies.
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