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Biological Activity
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.26 mL | 141.3 mL | 282.61 mL |
| 0.5 mM | 5.65 mL | 28.26 mL | 56.52 mL |
| 1 mM | 2.83 mL | 14.13 mL | 28.26 mL |
| 5 mM | 0.57 mL | 2.83 mL | 5.65 mL |
*The above data is based on the productmolecular weight 353.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21790 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 956025-47-1 |
| Formula | C19H20ClN5 |
| M. Wt | 353.85 |
| Purity | >98% |
| Synonyms | 1-NA-PP 1 hydrochloride |
| SMILES | CC(N1N=C(C2=C3C=CC=CC3=CC=C2)C4=C(N)N=CN=C41)(C)C.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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