[10]-Shogaol is a potent orally active antioxidant, primarily targeting pro-inflammatory pathways. Derived from ginger (Zingiber officinale), it inhibits cyclooxygenase-2 (COX-2) with an IC50 of 7.5 μM, reducing the production of pro-inflammatory cytokines such as IL-1β and IL-6, and suppressing NF-κB phosphorylation. This compound exhibits notable anti-inflammatory and anticancer activities, particularly against Docetaxel-resistant prostate cancer. Additionally, [10]-Shogaol demonstrates larvicidal efficacy against L5 larvae of Angiostrongylus cantonensis, making it useful for diverse biological research applications.
[10]-Shogaol is a potent orally active antioxidant, primarily targeting pro-inflammatory pathways. Derived from ginger (Zingiber officinale), it inhibits cyclooxygenase-2 (COX-2) with an IC50 of 7.5 μM, reducing the production of pro-inflammatory cytokines such as IL-1β and IL-6, and suppressing NF-κB phosphorylation. This compound exhibits notable anti-inflammatory and anticancer activities, particularly against Docetaxel-resistant prostate cancer. Additionally, [10]-Shogaol demonstrates larvicidal efficacy against L5 larvae of Angiostrongylus cantonensis, making it useful for diverse biological research applications.
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![[10]-Shogaol 36752-54-2 Antioxidant](https://www.adooq.com/media/catalog/product/cache/9222bce87e7def4079ba2ab8616be292/a/3/a35832-10-shogaol.gif)
