11-Desethyl Irinotecan

Catalog No.: A70388
Alkaloid
11-Desethyl Irinotecan is a camptothecin (CPT) analog and a significant metabolite of irinotecan, targeting topoisomerase I. This compound exhibits potent antitumor activity and is instrumental in cancer research, offering insights into therapeutic applications and metabolism of CPT derivatives. Its pharmacological profile makes it a valuable tool for studying mechanisms of chemotherapy resistance and evaluating efficacy in various cancer models.
Grouped product items
Size Price Stock Qty
5mg
$70.00
In stock
10mg
$110.00
In stock
25mg
$195.00
In stock
50mg
$295.00
In stock
100mg
$450.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description11-Desethyl Irinotecan is a camptothecin (CPT) analog and a significant metabolite of irinotecan, targeting topoisomerase I. This compound exhibits potent antitumor activity and is instrumental in cancer research, offering insights into therapeutic applications and metabolism of CPT derivatives. Its pharmacological profile makes it a valuable tool for studying mechanisms of chemotherapy resistance and evaluating efficacy in various cancer models.
Product Information
Catalog NumA70388
FormulaC31H34N4O6
Molecular Weight558.62
CAS Number103816-16-6
SMILESO=C1N2C(C(C(C2)=CC3=C4)=NC3=CC=C4OC(N5CCC(N6CCCCC6)CC5)=O)=CC7=C1COC([C@]7(O)CC)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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